For adults with chronic moderate to severe plaque psoriasis Clearer skin
Example of approximately 75% skin clearance after 3 months. For illustrative purposes only. Your results may vary. Prescription ENBREL is an injection that is clinically proven to provide clearer skin. In medical studies, nearly half of patients saw 75% skin clearance at 3 months. Overall, 3 out of 4 patients saw 50% skin clearance at 3 months. Your results may vary. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL, including tuberculosis (TB).
ENBREL is indicated for the treatment of adult ENBREL treatment, even if you have tested negative forTB. • Have diabetes, HIV, or a weak immune system patients (18 years or older) with chronic moderate to There have been some cases of unusual cancers reported in • Have TB or have been in close contact with someone who severe plaque psoriasis who are candidates for children and teenage patients who started using tumor has had TB systemic therapy or phototherapy. necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including • there Were born is more in, risk lived for in, getting or traveled TB. Ask your to countries doctor if you where are ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA or psoriasis may be more likely not sure to get lymphoma. • Live, have lived in, or traveled to certain parts of the country medicine that affects your immune system. Before starting ENBREL, tell your doctor if you Southwest) (such as, the where Ohio there and is Mississippi a greater risk River for certain valleys, kinds or the of ENBREL can lower the ability of your immune system to fight • Have any existing medical conditions fungal infections, such as histoplasmosis. These Infections infections. Serious infections have happened in patients may develop or become more severe if you take ENBREL. If taking ENBREL. These infections include tuberculosis (TB) and • Are taking any medicines, including herbáis you don't know If these infections are common in the areas infections caused by viruses, fungi, or bacteria that have spread • Think you have, are being treated for, have signs of, or are you’ve been to, ask your doctor throughout the body. Some patients have died from these prone to infection. You should not start taking ENBREL if you infections. Your doctor should test you for TB before you take have any kind of infection, unless your doctor says it is okay • Have or have had hepatitis B ENBREL and monitor you closely for TB before, during, and after • Have any open cuts or sores • Have or have had heart failure
No out-of-pocket cost for 6 months* If you and your doctor decide that ENBREL is right for you, ask about help with out-of-pocket costs through ENBREL Support™. Eligible patients can receive up to $4,000 of assistance Medicaid, etc.) or where prohibited by law. Restrictions, for each 6-month period/ Patient is responsible for including monthly maximums, may apply. Offer subject costs above these amounts. to change or discontinuation without notice. This is 'Eligibility: Open to patients with commercial prescription not health insurance. insurance. Not open to uninsured patients or patients +For patients with moderate to severe plaque psoriasis, receiving prescription reimbursement under any federal, who are first starting ENBREL and prescribed 50 mg state, or government-funded insurance programs twice-weekly dosing, program provides an additional (for example, Medicare including Medicare Part D, $2,000 per patient for the first 3 months of therapy only. Ask your dermatologist if ENBREL is right for you. Learn more: Visit AboutEnbrel.com or call 1-888-4ENBREL.
• Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL • Use the medicine Kineret® (anaklnra), Orencia® (abatacept), or Cytoxan® (cyclophosphamide) • Are taking anti-diabetic medicines • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome • Are scheduled to have surgery • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines. • Are allergic to rubber or latex
• Are pregnant, planning to become pregnant, or breastfeeding • Have been around someone with chicken pox What are the possible side effects of ENBREL? ENBREL can cause serious side effects Including: New infections or worsening of Infections you already have; hepatitis B can become active if you already have had It; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis. Common side effects include: Injection site reactions, upper respiratory Infections (sinus Infections), and headache. These are not all the side effects with ENBREL. Tell your doctor
about any side effect that bothers you or does not go away. If you have any questions about this Information, be sure to discuss them with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Please see Medication Guide on the following page. ©2012 Amgen Inc., Thousand Oaks, CA 91320 and Pfizer Inc. All rights reserved. 60028-R3-V3 08/12